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Senator Tom Tillisone of two Republicans votes against the president’s advance Donald Trump’s “The Big and Beautiful Bill” is expected to retire from the Senate at the end of his term.
North Carolina Republicans announced on Sunday that they will not seek re-election in the 2026 cycle. Tillis will be one of the most vulnerable Republicans next year and will face the threat of facing a challenger from Trump after a vote against the president’s agenda on Saturday night.
Key GOP Senators are flawed in key votes, narrow majority of Trump’s “big, beautiful bills”

Senator Tom Tillis (Getty Images)
Lawmakers are likely to vote against moving forward in the bill and against the final passage.
In a statement, Tillis opposed the slow, bipartisan death in Washington.
“Over the past few years, it has become increasingly clear in Washington that leaders are willing to embrace bipartisanship, compromise and demonstrate that independent thinking is becoming an endangered species,” he said.

President Donald Trump smiles at the Turning Point USA American Fest at the Phoenix Convention Center held in Phoenix on December 22, 2024. (Rebecca Noble/Getty Images)
Tillis screamed to Senator Joe Manchin and Kirsten Cinema for their dislike of “stopping into the boss of their party to nuke the filibuster for political convenience.”
“They eventually retired and their presence as Senators has been overlooked every day ever since,” he said.
“It underscores the hypocrisy of the greatest hypocrisy in American politics. When people saw independent thinking on the other side, they cheered on,” he continued. “But when they see the independent thoughts that come from their side, they are corned, exiled, and even blamed them.”
He said the choice broke to spend time with his family or spend six more years in Washington navigating “political theatre and partisan gridlock.”
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Senate majority leader John Tune, Rs.D. will be seen after a Senate luncheon at the U.S. Capitol on Tuesday, June 24th, 2025. (Tom Williams/CQ-Roll Call, Inc, Getty Images)
“That’s not a difficult choice. I’m not seeking reelection,” he said.
But Tillis has given Trump room for the next 18 months, as he did earlier this year when he refused to support Ed Martin, the presidential election as US lawyer for the District of Columbia. The decision abandoned Martin’s nomination.
“I look forward to having the pure freedom to call balls and strikes like I think I’m healthy,” he said.
His decision to retire anything likely to become a competitive race in North Carolina, and Democrats will soon be trying to hit him.
Mave Coyle, a spokesman for the Democratic Senate Campaign Committee, said in a statement shortly after Tillis’ decision, “his choice not to run for reelection will take another blow as Republicans face medium-term backlash that puts their majority at risk.”
“Even Tillis has acknowledged the GOP plan to reduce Medicaid and spike costs for families. In 2026, Democrats will overturn North Carolina’s Senate seats,” she said.
But Tim Scott, Rs.C., chairman of the National Republican Senate Committee. argued that Trump has won three North Carolina states and remains a major factor in the mid-cycle going forward, given that the state has been represented by two Republican senators for more than a decade.
“That streak will continue in 2026 when North Carolinians select conservative leaders who are committed to promoting an agenda of opportunity, prosperity and safety,” he said.
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It also comes after the Vice President vowed to blow up most of Saturday evening Tillis as a ‘ancestor’ and interview potential major challengers. jd vanceSenate majority leader John TuneRs.D. , and his leadership team worked through the Holdout Finance Hawks.
“Many people wanted to run the primary against Senator Tom Tillis,” Trump said in The Truth Society. “I will be meeting them over the next few weeks to find the great people of North Carolina and, importantly, the United States of America. Thank you for paying attention to this issue!”