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Coenzyme Q10, better known as CoQ10, boosts energy and heart health — But how do the benefits and risks stack up?
CoQ10 is a natural compound found in every cell that helps turn food into usable energy. According to multiple health sources, it also acts as an antioxidant, helping protect cells from everyday wear and tear.
Because CoQ10 levels naturally decline with age and can decline further with the use of certain medications, many people reach for supplements, which are often marketed over-the-counter for heart health, energy, muscle recovery, and even brain protection.
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But before you add that bottle to your cart, here’s what cardiologists and health experts have to say about it:
According to the National Center for Complementary and Integrative Health (NCCIH), CoQ10 plays an important role in the body, but there is no conclusive clinical evidence that it can broadly prevent or treat disease.

Coenzyme Q10 levels decline with age, which is why many people turn to supplements. (St. Petersburg)
Some studies suggest that CoQ10 may slightly lower blood pressure or reduce the fatigue caused by prescription drugs that lower cholesterol, but large, well-designed trials have not found significant effects on Parkinson’s disease, heart disease, or other conditions.
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Still, experts say CoQ10 is considered safe for most people. The main side effects are mild, such as an upset stomach and insomnia, but NCCIH warns that supplements can interfere with side effects. certain medicinessuch as blood thinners and insulin.
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Cardiologists are interested but cautious. A 2022 American College of Cardiology (ACC) press release states that CoQ10 is one of the few micronutrients that may lead to lower cardiovascular risk and lower all-cause mortality.
However, the same release stressed that more high-quality research is needed before that happens. Doctors can recommend it Overall.

Cardiologists recommend consulting your doctor before adding CoQ10 to your plan. (St. Petersburg)
Coenzyme Q10 can relax blood vessels, which could lower blood pressure lower than expected in some cases, experts warn.
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Unlike prescription drugs, supplements are not tightly regulated by the FDA. This means that the amount of CoQ10 in each capsule can vary greatly from brand to brand.
We recommend that you look for products that are Third party testedsuch as those with the USP (United States Pharmacopeia) seal to ensure quality and purity.
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According to the National Institutes of Health, CoQ10 is fat-soluble, so it must be taken with a meal containing healthy fats for better absorption.
Most people tolerate 100 mg to 200 mg of CoQ10 per day without issue. However, experts advise consulting your doctor to determine the appropriate dosage.

Coenzyme Q10 supplements sold over the counter are not regulated like prescription drugs. (St. Petersburg)
Experts agree that while Coenzyme Q10 is generally safe and has some benefits, it is not a miracle drug.
According to the Mayo Clinic, people with heart failure or frequent migraines may benefit from supplements, but should talk to their doctor first.
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For people looking to improve their heart health, the best bet remains the following therapies: regular exercisea balanced diet and care under medical supervision.